Hypothermic myxedema coma erroneously diagnosed as myocardial infarction because of increased creatine kinase MB
Nee, P.A.; Scane, A.C.; Lavelle, P.H.; Fellows, I.W.; Hill, P.G.
Clinical Chemistry 33(6): 1083-1084
1987
ISSN/ISBN: 0009-9147 PMID: 3594803 Document Number: 293708
As is well recognized, activities of creatine kinase (CK, EC 2.7.3.2) and lactate dehydrogenase (EC 1.1.1.27) in plasma may be substantially increased in hypothyroidism. We emphasize here that an increase and decrease in CK-MB isoenzyme, characteristic of acute myocardial infarction, can occur in hypothermic myxedema coma without myocardial infarction.