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Lack of enzyme polymorphism in Trypanosoma rangeli stocks from sylvatic and domiciliary transmission cycles in Colombia

Holguín, A.F.; Saravia, N.G.; D'Alessandro, A.

American Journal of Tropical Medicine and Hygiene 36(1): 53-58

1987

ISSN/ISBN: 0002-9637
PMID: 3812885
Document Number: 293303
Stocks of T. rangeli from Rhodnius prolixus and infected humans from areas of Colombia where both T. rangeli and T. cruzi are transmitted, displayed electrophoretically detectable polymorphism for only a single enzyme, isocitrate dehydrogenase. This contrasts with the marked phenotypic heterogeneity previously reported among the T. cruzi stocks. The relatively restricted diversity manifested by stocks from different geographic sites and ecological habitats may reflect the existence of distinctive biologic or genetic constraints influencing T. cruzi and T. rangeli transmission.

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