Possibilities for defining dysplastic changes in the gastric mucosa during cytologic studies of gastric biopsies
Lukina, T.A.; Chistiakova, O.V.; Rottenberg, V.I.; Nechipaĭ, A.M.
Arkhiv Patologii 49(1): 32-37
1987
ISSN/ISBN: 0004-1955 PMID: 3827631 Document Number: 293064
The authors compared the data of cytologic and histologic studies of gastric biopsy material from 95 patients with different degree of epithelial dysplasia revealed histologically. Differentiation impairment and epithelial cell atypia can be revealed in cytologic preparations; basing on these features epithelial dysplasia was diagnosed cytologically in 40 patients (30 of them with adenomas). Cytological and histological diagnosis of epithelial dysplasia did not fully coincide. The most reliable are the cytological features of severe dysplasia, thus the main goal of a morphologic study is achieved. One should not identify the term "dysplasia" in a cytologic study with a term "proliferation". Gastric biopsy material may have the following cytologic characteristics: tegmental-fossa epithelium proliferation, marked proliferation of tegmental-fossa epithelium with atypia, epithelial dysplasia and such epithelial dysplasia when cancer is not ruled out.