Radiographic chest findings and clinical correlations in leptospirosis
Chawalparit, O.; Charoensak, A.; Niwattayakul, K.; Suttinont, C.; Losuwanaluk, K.; Silpasakorn, S.; Suputtamongkol, Y.
Journal of the Medical Association of Thailand 90(5): 918-924
2007
ISSN/ISBN: 0125-2208 PMID: 17596046 Document Number: 2915
Objective: To determine the clinical presentations, radiographic chest findings, and their correlation in patients with leptospirosis.Design: A cross sectional study.Setting: Between July 2001- December 2002 at 3 hospitals in North Eastern Thailand.Material and Method. Two hundred and forty patients with laboratory confirmed leptospirosis.Results: Two hundred and nine (8 7. 1 %) patients were males. The mean age was 3 7.53 years (range 13- 76). The median duration of fever was 3 days (range 1- 13). Overall, 154 patients (64.2%) had respiratory symptoms and 26 (10.8%) patients had hemoptysis. Jaundice was detected in 76 (31.7%) patients, hypotension in 50 (20.8%), renal dysfunction in 80 (30%), and multiorgan dysfunction in 62 (25.8%) on admission. One hundred and fifty-four (64.17%) patients had abnormal chest radiographs on admission (classified as cardiovascular, pulmonary, and mixed cardio-pulmonary involvement in 40 (25.97%), 41 (26.62%), and 73 (47.4%) patients, respectively). Jaundice was significantly associated with the likelihood of having abnormal chest radiography on admission. Air-space nodules detected on the chest radiograph were significantly more common in patients with renal dysfunction and patients who required mechanical ventilation.Conclusion: Pulmonary and cardiovascular involvements are common in leptospirosis. Air-space nodules detected by chest radiography may indicate severe leptospirosis.
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