In vivo and in vitro granulocyte migration in patients with extrinsic and intrinsic bronchial asthma
Matusiewicz, R.; Rusiecka-Matusiewicz, K.
Annals of Allergy 58(6): 425-428
1987
ISSN/ISBN: 0003-4738 PMID: 3296868 Document Number: 291129
Sixty-five patients with atopic asthma, 54 with infectious asthma, and 30 healthy controls were evaluated by in vitro granulocyte migration and by the in vivo skin window method of Southam. Quantitative IgM, IgG, IgA, IgE serum concentrations were measured. In vivo migration of granulocytes was decreased in patients with atopic asthma and elevated levels of IgE as well as in patients with infectious asthma and elevated levels of IgG. In vivo migration of granulocytes showed significant decreases in both asthmatic groups only during asthmatic attacks.