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Identification of a metabolite of floctafenine in urinary calculi

Moesch, C.; Rince, M.; Raby, C.; Leroux-Robert, C.

Annales de Biologie Clinique 45(5): 546-550

1987

ISSN/ISBN: 0003-3898
PMID: 2892454
Document Number: 291018
There are three 4-amino-quinolines used for their analgesic properties: glafenine, antrafenine and floctafenin. Urinary calculi due to glafenine have been described since 1980. Recently two cases of renal calculi containing antrafenic acid have been reported. We discovered a metabolite of floctafenin in a bladder calculus and describe its identification by infrared spectrophotometry and thin-layer chromatography.

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