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Intensive plasmapheresis--possible difficulties and complications

Ryzhko, V.V.; Gorodetskií, V.M.; Borisov, B.A.

Terapevticheskii Arkhiv 59(6): 70-75

1987

ISSN/ISBN: 0040-3660
PMID: 3629503
Document Number: 290004
The paper is concerned with an analysis of difficulties and complications resulting from various modes of conducting intensive plasmapheresis using mainly refrigerator centrifuges and plasticized resin containers in 462 patients (a total of 2435 procedures). Emphasis was placed on a necessity of a thorough choice of a vascular access with relation to a patient's condition, a more of plasmapheresis, and an assumed volume of plasma removal. Causes of hemodynamic and temperature reactions, "citrate intoxication" were analyzed; their prevention and therapy were described. Plasmapheresis was accompanied by insignificant variations in the level of leukocytes, platelets, normal immunoglobulins and fibrinogen. Complications during plasmapheresis were often related with the stage of plasmosubstitution.

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