Isotretinoin treatment of rosacea
Turjanmaa, K.; Reunala, T.
Acta Dermato-Venereologica 67(1): 89-91
1987
ISSN/ISBN: 0001-5555 PMID: 2436425 Document Number: 288254
Twenty patients with severe rosacea were treated with isotretinoin for 3-6 months. Six patients initially received 1.0 mg/kg and 14 patients 0.5 mg/kg of isotretinoin. The response was good or excellent in all patients and the papulopustular lesions in particular cleared promptly. Patients receiving 1.0 mg/kg of isotretinoin experienced more side-effects and the dose had to be lowered in five of the six patients. Seventeen of the 20 patients had no relapses during a follow-up of one year showing that isotretinoin has a long-lasting favourable effect in rosacea.