Improving the response to gold or D-penicillamine by addition of sulphasalazine. a pilot study in 25 patients with rheumatoid arthritis
Dawes, P.T.; Sheeran, T.P.; Fowler, P.D.; Shadforth, M.F.
Clinical and Experimental Rheumatology 5(2): 151-153
1987
ISSN/ISBN: 0392-856X PMID: 2886241 Document Number: 288192
In a 6-month open pilot study 25 patients with Rheumatoid Arthritis (RA) whose disease was refractory to Gold or D-Penicillamine (DPA) were given Sulphasalazine (SAS) in addition. Three patients withdrew because of nausea. Twenty-two patients who completed therapy showed significant improvement in clinical and laboratory measures of disease activity.