Role of changes in the hormonal system of the gastrointestinal tract after vagotomy
Shvarts, V.I.; Kuznetsov, B.G.; Frolkov, V.K.
Terapevticheskii Arkhiv 59(2): 39-44
1987
ISSN/ISBN: 0040-3660 PMID: 3554589 Document Number: 287453
The level of gastrin, serotonin, insulin and cortisol in the blood was raised after different types of vagotomy. Raised hormone secretion depends on the time following operation, the severity of a pathological process, to a lesser degree, on the type of surgical intervention and nature of postvagotomic disturbance. Shifts in the hormonal apparatus are caused by operation and associated with it functional-morphological changes of the digestive organs, the preservation of preoperative changes and developing compensatory-adaptive reactions. An excess of intestinal hormone secretion in the postoperative period can be responsible for the development of pathological disorders, in particular the dumping syndrome.