Uneven fractionation irradiation
Kamata, R.; Urahashi, S.; Sanuki, E.; Sato, K.; Kumagai, Y.; Saito, T.; Takashima, H.; Shimada, Y.; Maeno, T.; Kawamori, J.
Gan no Rinsho. Japan Journal of Cancer Clinics 33(13): 1591-1600
1987
ISSN/ISBN: 0021-4949 PMID: 3121890 Document Number: 287277
To get the better therapeutic ratio with low LET radiation therapy alone, the improvement of the physical dose distribution and the mode of dose fractionation are required. Since 1972, uneven fractionation irradiation with electron beam has been used for head and neck tumors. The 2 year control rates for primary tongue cancer T1, T2 and T3 by this method were approximately comparable to that of the small source implantation. In the treatment results for the cervical lymph node metastasis, uneven fractionation technique is superior to conventional one. Furthermore, this results was reviewed by means of multivariate analysis.