Risk factors for HIV-1 and HIV-2 infection in pregnant women in Dakar, Senegal
Abbott, R.C.; NDour-Sarr, A.; Diouf, A.; NDoye, T.; Bâ, D.; Tall, N.; MBaye, N.; Kébé, F.; Diadhiou, F.; Essex, M.E.
Journal of Acquired Immune Deficiency Syndromes 7(7): 711-717
1994
ISSN/ISBN: 0894-9255 PMID: 8207649 Document Number: 286955
This study examines the prevalence and risk factors for Human Immunodeficiency Virus type 1 (HIV-1) and type 2 (HIV-2) infection in pregnant women in Dakar, Senegal. From April 1991 to January 1993, 9,518 pregnant women were interviewed and serologically tested for antibodies to HIV-1 and HIV-2; 26 (0.3%) were HIV-1 seropositive, 44 (0.5%) were HIV-2 seropositive, two (0.02%) were dually seropositive, and 9,448 (99.3%) were seronegative. Guinea-Bissau nationality and age > 25 years were associated with HIV-2 infection, whereas parity < or = 2 was associated with HIV-1 infection. Among women who gave birth to live infants, shorter length of union with the partner and having been married more than once were associated with HIV-2 infection, whereas age < or = 25 years was associated with HIV-1 infection. Information gained by this study may help target intervention strategies for preventing maternal HIV infection and understanding biological differences between the two viruses.