Oxygen regimen of rat kidneys in regeneration and carcinogenesis
Beliaeva, N.M.; Nikolaev, V.P.; Matchin, G.A.
Voprosy Onkologii 32(4): 65-68
1986
ISSN/ISBN: 0507-3758 PMID: 3705530 Document Number: 286067
Oxygen tension in the kidneys in compensatory hyperplasia after nephrectomy and in renal carcinogenesis induced by nitrosodimethylamine was studied in 80 albino noninbred rats. Regeneration and malignant transformation were found to involve similar changes in oxygen conditions in rat's kidneys, viz. disturbances in the function of microvessels and decreased utilization of oxygen.
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