Intolerance to metoclopramide (apropos of 22 case reports of infants of the black race)
Imbert, P.; Burguet, A.; Teyssier, J.
Medecine Tropicale Revue du Corps de Sante Colonial 46(2): 155-158
1986
ISSN/ISBN: 0025-682X PMID: 3724413 Document Number: 285705
The authors report on 22 observations made from june 1982 to december 1984 in African children having presented an intolerance against metoclopramide. After recalling briefly the pharmacology of this drug, they describe the symptomatology similar to neuroleptic intoxication syndrome: parkinsonian syndrome, motor excitation syndrome. Posology was correct in 2/3 of the cases, when it was known. Overdose was observed in 5 cases only. Recovery was complete after the administration of the drug was stopped, but it was accelerated by antiparkinsonian drugs.