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Effect of the complex treatment of stable stenocardia on the status of the prostacyclin-thromboxane system

Khimenko, P.L.

Terapevticheskii Arkhiv 58(5): 95-98

1986

ISSN/ISBN: 0040-3660
PMID: 2874621
Document Number: 285271
Raised function of platelets with an increase in their aggregation activity in vitro and an increase in spontaneous intravascular activation as well as imbalance of the prostacyclin-thromboxane system with a shift to the predominance of proaggregation agents were detected in CHD patients after myocardial infarction suffering from stable angina. An inhibiting effect of beta-adrenergic receptor blocking agents and acetylsalicylic acid on the synthesis of thromboxane A2 was observed. No marked effect of dipyridamole on the prostacyclin-thromboxane system was noted.

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