Atrial natriuretic peptide. new aspects in the regulation of blood volume and electrolyte homeostasis
Tulassay, T.; Rascher, W.
Monatsschrift Kinderheilkunde Organ der Deutschen Gesellschaft für Kinderheilkunde 134(10): 710-715
1986
ISSN/ISBN: 0026-9298 PMID: 2948113 Document Number: 281164
Atrial natriuretic peptide (ANP) is a newly discovered hormone released from cardiac atrial myocytes into the circulation. Secretion of the hormone is triggered by atrial distension and volume overload. ANP consist of 28 aminoacids. The hormone induces natriuresis, diuresis and increases glomerular filtration rate. Moreover, it dilates vascular smooth muscle and opposes the effects of several vasoactive hormones. Thus ANP plays an important role in the regulation of body fluids and electrolyte homeostasis.