Suppression of persistent varicella-zoster virus infection in Vero cells by acyclovir
Pérez Martín, C.; Vilas Minondo, P.; García Gancedo, A.; Pérez Prieto, S.I.
Acta Virologica 30(4): 341-345
1986
ISSN/ISBN: 0001-723X PMID: 2876616 Document Number: 280160
Persistent infection was established in Vero cells inoculated with varicella-zoster virus (VZV)-infected WI-38 cells. Treatment with 9-(2-hydroxy-ethoxymethyl)guanine (acyclovir) at doses of 100, 80, 40, and 10 micrograms/ml eliminated the infectious virus, lower doses such as 0.1 and 0.01 micrograms/ml were ineffective.
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