DNA metabolism during maturation of male germ cells. II. Amplification structures in the nuclei of rat germ and somatic cells
Glazkov, M.V.
Genetika 22(10): 2430-2438
1986
ISSN/ISBN: 0016-6758 PMID: 3792837 Document Number: 280138
Amplification structures have been found in preparations of histone-depleted somatic (liver) and sex (spermatogonia, spermatocytes 1) rat cells. Multi-forked chromosomal (2-4 replicative forks originating from a single strand of DNA) and extrachromosomal circular amplification structures have been detected in the nuclei of sex cells. All the circular molecules of DNA detected belong, according to size, to the class of small nuclear polydispersed circular DNAs. Chromosomal amplification structures (eye-in-eye or several replicative forks originating from one DNA strand) have been only detected in the nuclei of somatic cells.