Prospective randomized study of the efficacy of adjuvant hormone therapy in patients with breast cancer
Semiglazov, V.F.; Moiseenko, V.M.; Ivanova, O.A.
Voprosy Onkologii 32(8): 31-34
1986
ISSN/ISBN: 0507-3758 PMID: 3532535 Document Number: 279750
Tentative results of a randomized controlled evaluation of the effectiveness of adjuvant hormonal therapy of breast cancer are discussed. The data on 118 cases examined in 1981-1984 were considered on the basis of menstrual cycle characteristics and extension of tumor. The results obtained as a result of an average 16.9 month-long examination pointed to a relatively higher recurrence incidence in untreated patients and suggested that such studies should be continued. Tolerance evaluation established a higher incidence of side-effects in cases treated with diethylstilbestrol (33.3%) than with tamoxifen (3.8%).
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