Hand-Schüller-Christian syndrome arising in the mandible. A case report

Marchetti, C.; Ercolani, G.; Gibelli, R.; Donati, D.; Catani, F.

Minerva Medica 77(28-29): 1385-1391

1986


ISSN/ISBN: 0026-4806
PMID: 3736975
Document Number: 279481
The history of Letterer-Siwe, Hand-Schüller-Christian disease, and eosinophilic granuloma of the bone, and the evolution of the concept of grouping them together under the common term of histiocytosis X are presented. The characteristics of the disease, with particular emphasis on oral manifestations, are reviewed. The therapy for the disease is briefly outlined. One case of Hand-Schüller-Christian syndrome is presented. The discussion is focused on the problem of chemotherapy in disseminated forms.

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