Infection with group C rotavirus in a suburban community in Brazil
Cox, M.J.; James, V.L.; Azevedo, R.S.; Massad, E.; Medley, G.F.
Tropical Medicine and International Health Tm and Ih 3(11): 891-895
1998
ISSN/ISBN: 1360-2276 PMID: 9855402 DOI: 10.1046/j.1365-3156.1998.00325.xDocument Number: 279066
Group C rotaviruses are associated with sporadic outbreaks of gastroenteritis worldwide. Age-specific seroprevalence of group C rotavirus antibodies was investigated in sera, randomly collected and representative of a suburban community in Brazil which had previously been screened for group A rotavirus antibodies. Antibody prevalence to group C rotavirus was low in children under 5 years and increased slowly with age to 36% seropositivity in adults, reflecting continuous exposure to primary infection in all age groups. This suggests a higher incidence of infection than disease might predict. Adult antibody prevalence was similar to that in other geographical settings. No obvious patterns of infection with group A and group C rotavirus were found within individuals, which suggests independent transmission. However, further epidemiological studies are required to understand group C rotavirus dynamics and possible interactions with group A rotavirus transmission and immunity.