Influence of pregnancy, birth and abortion on the evolution of systemic lupus erythematosus
Mitu, S.; Purice, S.; Popescu, T.; Guran, M.; Vintilă, M.; Cojocaru, M.; Popescu, C.; Nistor, S.; Dumitrescu, C.
Medecine Interne 24(1): 55-60
1986
ISSN/ISBN: 0377-1202 PMID: 3704504 Document Number: 277764
The effect of pregnancy, birth and abortion on systemic lupus erythematosus (SLE) was studied in 225 patients with or without a history of pregnancy and abortion. It was observed that pregnancy, birth and abortion aggravate the evolution of disease in patients with active SLE. The tissue autoantibodies studies presented a low titer in patients in whom pregnancy had occurred in the course of disease. Antimeasles antibodies presented a high titer in patients with a history of gestation. These data suggest that gestation induces immune changes which aggravate SLE.