Uncomplicated falciparum malaria complicated by Salmonella septicaemia: cause not coincidence

Kanjilal, S.Datta.; Dutta, A.; Mondal, R.K.; Chakravorti, S.

Journal of the Indian Medical Association 104(11): 646 648

2006


ISSN/ISBN: 0019-5847
PMID: 17444068
Document Number: 2743
A 10-year-old boy presented with high-grade intermittent fever for 6 days with occasional vomiting and headache for 4 days [India]. He had mild pallor and splenomegaly. Peripheral smear examination confirmed the diagnosis of uncomplicated malaria caused by Plasmodium falciparum, and quinine treatment was initiated. He showed clinical improvement. However, on the 14th day of illness, a rise in temperature was observed. On examination, he was febrile with toxic look. There was gaseous distension of the abdomen and a mild tenderness was felt over the umbilical area. His haemoglobin level and total leukocyte count were 6.8 g/dl and 8400/ml, respectively. A repeat peripheral smear examination was negative for malaria parasite, but blood culture grew Salmonella typhi. He was given ceftriaxone as treatment for Salmonella septicaemia. His fever and abdominal symptoms gradually subsided. He became afebrile after 6 days of treatment and was subsequently discharged.

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Uncomplicated falciparum malaria complicated by Salmonella septicaemia: cause not coincidence