Hypercalcemia in childhood. a boy with asymptomatic hypocalciuric hypercalcemia
Van Steensel-Moll, H.A.; Drop, S.L.
Tijdschrift Voor Kindergeneeskunde 54(5): 147-150
1986
ISSN/ISBN: 0376-7442 PMID: 3026063 Document Number: 271843
The diagnostic work-up of a patient with (familial) hypocalciuric hypercalcemia (FHH) is discussed. The patient showed no clinical signs of hypercalcemia. There were no indications of vitamin D intoxication. In the first degree family members no hypercalcemia was found. Physical examination was normal. In contrast to hyperparathyroidism, FHH is usually symptomless. Furthermore, FHH is characterized by a normal chloride/phosphate ratio, a normal, but relatively high, serum parathyroid hormone level, a relatively low urinary calcium excretion, a calcium-creatinine clearance ratio less than 0.01 and a normal cyclic AMP excretion.