Persistent neurological syndrome after treatment with lithium salts. Toxicity of the lithium-neuroleptic combination?
Habib, M.; Khalil, R.; le Pensec-Bertrand, D.; Ali-Cherif, A.; Bongrand, M.C.; Crevat, A.
Revue Neurologique (Paris) 142(1): 61-64
1986
ISSN/ISBN: 0035-3787 PMID: 2871617 Document Number: 271662
In 2 patients receiving a long-term lithium carbonate therapy, persistent cerebellar, pyramidal, and extrapyramidal signs were observed, following a febrile pulmonary event. The mechanism of these disturbances is discussed, emphasizing the lithium-neuroleptics interaction as well as the possible role of hyperthermia.