Fatal fulminant hepatitis associated with Ganoderma lucidum (Lingzhi) mushroom powder

Wanmuang, H.; Leopairut, J.; Kositchaiwat, C.; Wananukul, W.; Bunyaratvej, S.

Journal of the Medical Association of Thailand 90(1): 179-181

2007


ISSN/ISBN: 0125-2208
PMID: 17621752
Document Number: 2708
Hepatotoxic effect related to Ganoderma lucidum (Lingzhi) mushroom powder was first described in a patient from Hong Kong in 2004. In 2005, the authors experienced a case of fatal fulminant hepatitis associated with such a preparation. Both patients had taken other therapeutic agents and traditionally boiled Lingzhi without any toxic effect. After switching to taking Lingzhi in powder form for 1-2 months, the hepatotoxic episode occurred in both patients. The toxic role of Lingzhi powder needs close monitoring in the future, especially in combination with other drugs.

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Fatal fulminant hepatitis associated with Ganoderma lucidum (Lingzhi) mushroom powder