Influence of Anisotes trisulcus and Crepis rueppellii extracts on sites of bile formation in the rat
Lanhers, M.C.; Bertrand, I.; Fleurentin, J.; Lehr, P.R.; Pelt, J.M.
Arzneimittel-Forschung 36(5): 826-829
1986
ISSN/ISBN: 0004-4172 PMID: 3730017 Document Number: 270590
Anisotes trisulcus and Crepis rueppellii, two medicinal plants from Yemen, have been investigated for their hepatobiliary properties. A study of their choleretic effect and of sites of bile formation was carried out in the rat, by evaluation of bile flow, bile acids output and 14C-erythritol clearance. The data suggest that both extracts of these plants induce hypercholeresis, but Anisotes would stimulate the bile acid-dependent fraction and Crepis the bile acid-independent fraction.