Large-scale synthesis of flumolol, a short-acting beta-blocker
Gustafsson, B.B.; Nitenberg, T.
Acta Pharmaceutica Suecica 23(4): 241-244
1986
ISSN/ISBN: 0001-6675 PMID: 3799216 Document Number: 270564
.beta.-blockers containing an ester moiety can be used as short-acting drugs. This is due to the enzymatic cleavage of the ester bond. The synthesis of flumolol, on a five mol scale, is described. This product was approved for toxicological studies.
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