Changes in the immune system indices of diabetes mellitus patients
Potemkin, V.V.; Kadagidze, Z.G.; Veskova, T.K.; Derevnina, N.A.; Danilov, K.Iu.
Problemy Endokrinologii 32(1): 3-5
1986
ISSN/ISBN: 0375-9660 PMID: 3485281 Document Number: 270479
A decrease in the amount of T-lymphocytes and the total amount of lymphocytes in the peripheral blood occurs in diabetes mellitus patients with hyperglycemia over 150 mg%; a decrease in the amount of T-active lymphocytes occurs but in 350 mg% and upwards. A decrease in the amount of B-lymphocytes is noted in hyperglycemia over 200 mg%. The reaction of blast-cell transformation is sharply suppressed in a grave form of diabetes mellitus whereas in moderately grave conditions its decrease is less noticeable. It is assumed that disorder of cellular immunity can be one of the factors contributing to the development of pyoseptic diseases in diabetes mellitus patients.