Experimental and clinical studies on the effects of synthetic muramyldipeptide derivatives on viral and opportunistic infections

Yamamura, Y.; Ishihara, C.; Hamada, N.; Yamamoto, K.; Azuma, I.

Methods and Findings in Experimental and Clinical Pharmacology 8(1): 11-14

1986


ISSN/ISBN: 0379-0355
PMID: 3010013
Document Number: 270039
The efficacy of strearoyl-MDP derivatives, L18-MDP and MDP-Lys-18 against bacterial and viral infections in mice was examined. Both L18-MDP and MDP-Lys-L18 stimulated nonspecifically host-resistance against opportunistic infection with C. kutscheri in hydrocrotisone-treated mice against Sendai virus infection in mice.

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