Methotrexate Therapy For Psoriasis (A Preliminary Report)
Kaur, S.; Kaur, I.; Bhushnurmath, S.R.; Kumar, B.
Indian Journal of Dermatology Venereology and Leprology 52(3): 155-157
1986
ISSN/ISBN: 0378-6323 PMID: 28150597 Document Number: 268504
Fourteen patients, 9 males and 5 females with chronic severe intractable psoriasis resistant to conventional therapies were treated with methotrexate. Five had psoriatic erythroderma while 9 had extensive disease. Methotrexate therapy given orally in weekly single doses of 20-30 mg was effective in all cases. The side effects observed included nausea and vomiting headache, pain abdomen, diffuse alopecia and loss of appetite.