Chemical properties of the placental FC gamma receptor
Mikulska, J.; Lisowski, J.
Archivum Immunologiae et Therapiae Experimentalis 33(3): 413-417
1985
ISSN/ISBN: 0004-069X PMID: 2933010 Document Number: 266296
The carbohydrate and amino acid compositions of the purified Fc receptor from human placental trophoblasts are described. The placental receptor is a glycoprotein. The total content of carbohydrates in the receptor is 30% (w/w). The major carbohydrate components are galactose, N-acetylglucosamine, fucose, and mannose. The placental receptor has a high content of acidic amino acids and a relatively low number of aromatic and hydrophobic amino acid residues. The ratio of contents of hydrophilic to hydrophobic amino acids is 2:1. The hydrophilic nature of the receptor molecules is shown by charge-shift electrophoresis.