Extramammary Paget's disease of the perianal and perineal regions. Evidence of apocrine derivation
Merot, Y.; Mazoujian, G.; Pinkus, G.; Momtaz-T, K.; Murphy, G.F.
Archives of Dermatology 121(6): 750-752
1985
ISSN/ISBN: 0003-987X PMID: 2408584 Document Number: 266139
A case of perianal and perineal extramammary Paget's disease in a male is reported. The presence of gross cystic disease fluid protein--a new marker of apocrine epithelia--in Paget's cells provides additional insight into the histopathogenesis of this condition. This marker may be a valuable diagnostic adjunct in evaluating intra-epithelial malignancies at a variety of anatomic sites.