Effect of N-acetylcysteine on the ciliary beat frequency of human bronchial explants
Low, P.M.; Dulfano, M.J.; Luk, C.K.; Finch, P.J.
Annals of Allergy 54(4): 273-275
1985
ISSN/ISBN: 0003-4738 PMID: 3985421 Document Number: 262541
The effect of N-acetylcysteine on human bronchial cilia was evaluated by measuring the changes in ciliary beat frequency (CBF) on human bronchial explants exposed to 1%, 2%, 3%, 4%, and 5% concentrations of N-acetylcysteine solution in nutrient medium. There was a progressive reduction in CBF at increasing concentration, indicating an inhibitory effect on human ciliary activity in vitro (P less than 0.05).
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