Follow-up studies on children with severe dietary chloride deficiency during infancy
Hellerstein, S.; Duggan, E.; Merveille, O.; Scarth, L.
Pediatrics 75(1): 1-7
1985
ISSN/ISBN: 0031-4005 PMID: 3966031 Document Number: 262532
Ten children who had severe dietary chloride deficiency during early infancy have grown normally during their first 4 to 5 years. With the exception of 1 child who did not get into the sitting position alone until he was 9-1/2 months of age, the patients reached the usual developmental milestones of the first 2 years during the expected age intervals. Developmental and psychological testing indicates that all of the children have at least average ability. However, 3 children have shown behavior patterns that may interfere with successful school performance. Serum creatinine and urea nitrogen concentrations appear to be normal as does renal concentrating capacity. During a 4-year follow-up, 1 child has shown persistent and a second intermittent microscopic hematuria. (author)