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Perioperative single dose antibiotic therapy in elective surgery

Gardezi, S.A.; Chaudhry, A.M.; Sial, G.A.; Mahmood, K.

Jpma. Journal of the Pakistan Medical Association 35(4): 112-115

1985

ISSN/ISBN: 0030-9982
PMID: 3927023
Document Number: 261804
A placebo controlled study was undertaken to evaluate the role of antimicrobials as a single 24 hours cover peri-operatively. Patients matching in proposed surgery, age, sex, diagnosis and built were divided into three groups. Group 'A' was on plaecbo, group 'B' received full dose of antibiotics by conventional method and group 'C' received antibiotics as a single 24 hour cover perioperatively. The post operative incidence of complications was 27% in placebo, 13% in group 'B' and 7% in group 'C'. The perioperative use of antibiotics has been found to be comparatively more effective, safe and economical. (JPMA 35:112, 1985).

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