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Successful treatment of therapy-resistant pancreatic cholera with human leucocyte interferon

Oberg, K.; Alm, G.; Lindström, H.; Lundqvist, G.

Lancet 1(8431): 725-727

1985

ISSN/ISBN: 0140-6736
PMID: 2857998
Document Number: 260120
The pancreatic cholera syndrome is a serious and potentially fatal disease found in patients with endocrine pancreatic tumors and ganglioneuromas. Two patients with therapy-resistant pancreatic cholera syndrome were successfully treated with human leukocyte interferon given i.m. in a dose of 3 .times. 106-6 .times. 106 IU/day. This produced a reduction in stool volume and plasma vasoactive intestinal polypeptide (VIP) within 3-5 days of the start of treatment. Tumor mass decreased in 1 patient after 3 mo. of treatment but some tumor tissue remained after 15 mo. observation, although circulating concentrations of VIP were normal. The mechanisms of interferon action are not known but a direct inhibition of tumor-cell hormone production and perhaps of tumor cell proliferation might account for the rapid clinical response.

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Gröhn, P. 1989: Treatment of soft tissue sarcomas with interferon with special reference to general features of interferon therapy Acta Chirurgica Scandinavica. Supplementum 549: 50-51
Sakuma, I.; Enomoto, N.; Asahina, Y.; Kurosaki, M.; Sato, C. 1995: Fluctuation of hepatitis C virus quasispecies with interferon treatment and interferon-resistant variants in hepatitis C virus 1b Nihon Rinsho. Japanese Journal of Clinical Medicine 53 Suppl (Part 1): 930-935
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