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Frequency of finding the markers of hepatitis B virus infection in infants in the 1st year of life receiving a plasma transfusion

Sychev, A.V.; Mikhaĭlov, M.I.; Shakhgil'dian, I.V.; Golosova, T.V.; Vlasikhina, E.N.

Voprosy Virusologii 30(5): 553-558

1985

ISSN/ISBN: 0507-4088
PMID: 4072158
Document Number: 259803
The frequency of detection of HB virus infection markers was determined by sensitive methods (passive hemagglutination, immunofluorescence, radioimmunoassay) in 83 infants under 1 year receiving transfusions of HB-antigen-negative (by counter-current immunoelectrophoresis) plasma and regularly observed for one year. Among them, 12 (14.4%) infants were found to be infected with hepatitis B virus which was confirmed in 7.2% by the detection of transitory HBs-antigenemia, in 2.4% by the detection of anti-HBc alone which had not been found previously, and in 4.8% by the detection of anti-HBs- previously absent in the blood, including 2.4% with a combination of anti-HBs and anti-HBc. In one case (1.2%) hepatitis was accompanied by jaundice absent in 11 (13.2%) cases.

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