HIV-1 subtypes in Yugoslavia
Stanojevic, M.; Papa, A.; Papadimitriou, E.; Zerjav, S.; Jevtovic, D.; Salemovic, D.; Jovanovic, T.; Antoniadis, A.
Aids Research and Human Retroviruses 18(7): 519-522
2002
ISSN/ISBN: 0889-2229 PMID: 12015906 DOI: 10.1089/088922202317406673Document Number: 259675
To gain insight concerning the genetic diversity of HIV-1 viruses associated with the HIV-1 epidemic in Yugoslavia, 45 specimens from HIV-1-infected individuals were classified into subtypes by sequence-based phylogenetic analysis of the polymerase (pol) region of the viral genome. Forty-one of 45 specimens (91.2%) were identified as pol subtype B, 2 of 45 as subtype C (4.4%), 1 of 45 as CRF01_AE (2.2%), and 1 as CRF02_AG recombinant (2.2%). Nucleotide divergence among subtype B sequences was 4.8%. Results of this study show that among HIV-1-infected patients in Yugoslavia subtype B predominates (91.5%), whereas non-B subtypes are present at a low percentage, mostly related to travel abroad.