Use of recombinant factor VIIa for massive postpartum haemhorrage: case series and review of literature

Shamsi, T.Sultan.; Hossain, N.; Soomro, N.; Hasan, J.Ara.; Noorani, M.; Kazi, S.; Quraishy, M.Saeed.; Jameel, B.; Sultan, S.Tipu.; Haider, S.

Jpma. Journal of the Pakistan Medical Association 55(11): 512-515

2005


ISSN/ISBN: 0030-9982
PMID: 16304877
Document Number: 258757
Recombinant activated factor VII is indicated mainly for the treatment of patients with haemophilia inhibitors. It has also been found successful in the treatment of platelet disorder Glanzmann's thrombasthenia. Recently, its use in trauma patients and in patients with intracereberal haemorrhage has become well established. We present three cases of massive post partum haemorrhage treated with rFVIIa, following caesarean section. The response of these three patients is discussed along with review of literature.

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