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Cimetropium bromide, a new antispasmodic compound: pharmacology and therapeutic perspectives

Scarpignato, C.; Bianchi Porro, G.

International Journal of Clinical Pharmacology Research 5(6): 467-477

1985

ISSN/ISBN: 0251-1649
PMID: 3912339
Document Number: 258613
The pharmacology and clinical use of cimetropium bromide is reviewed. Experimental and clinical data demonstrated that this new compound is a potent antimuscarinic and an effective antispasmodic drug. It is also endowed of a direct myolitic action which partially accounts for its antispasmodic activity. Clinical trials as yet performed confirmed its efficacy in many painful conditions of the gastrointestinal, biliary and genitourinary tracts, as well as its usefulness as a pre-endoscopic medication. Finally, the drug proved to be well tolerated, with a low incidence of atropine-like untoward effects.

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Centonze, V.; Imbimbo, B.P.; Campanozzi, F.; Attolini, E.; Daniotti, S.; Albano, O. 1988: Oral cimetropium bromide, a new antimuscarinic drug, for long-term treatment of irritable bowel syndrome American Journal of Gastroenterology 83(11): 1262-1266
Silber, W. 1979: Prifinium bromide - a new antispasmodic South African Medical Journal 56(24): 1033-1034
Sunahara, F.A.; Herr, F. 1970: Pharmacology of an antispasmodic agent pentapiperide methylsulfate Archives Internationales de Pharmacodynamie et de Therapie 184(2): 287-298
Matsuda, H.; Kawaba, T.; Yamamoto, Y.; Ogawa, S. 1976: Absorption, distribution, excretion and metabolism of a basic ether compound (R97) with antispasmodic activity Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica 72(6): 657-672
Kubo, S.; Morikawa, K.; Matsubara, I.; Yamazaki, M.; Kato, H. 1981: Pharmacological studies of antispasmodics. III. Antispasmodic activity of 3-(di-2-thienylmethylene)-5-methyl-trans-quino-lizidinium bromide (HRS-902) on smooth muscle organs and its organ selectivity Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica 77(1): 87-98
Fukushima, K.; Miyashita, K. 1971: Clinical pharmacology of pancuronium bromide Masui. Japanese Journal of Anesthesiology 20(3): 235-239
Duchêne-Marullaz, P. 1977: Pharmacology, clinical pharmacology and therapeutic effects of Royat's thermal gas Semaine des Hopitaux. Therapeutique 53(7-8): 361-362
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Katsumi, T.; Murayama, K. 1992: Clinical effects of distigmine bromide (Ubretid), a cholinesterase inhibitor, on micturition disturbance by benign prostatic hypertrophy--comparative study of distigmine bromide and the combination of distigmine bromide and adrenergic blocker Hinyokika Kiyo. Acta Urologica Japonica 38(9): 1089-1092
Reynolds, J.R.; Reynolds, J.R. 2008: On the therapeutic uses of bromide of potassium. 1868 Practitioner 252(1711): 35
De Schaepdryver, A.F. 1992: Clinical pharmacology: current status and perspectives Verhandelingen - Koninklijke Academie Voor Geneeskunde van Belgie 54(1): 7-26
Shaw, N.; Trepanier, L.A.; Center, S.A.; Garland, S. 1996: High dietary chloride content associated with loss of therapeutic serum bromide concentrations in an epileptic dog Journal of the American Veterinary Medical Association 208(2): 234-236
Da Cunha, A.S.; da Silva, E.F.; Raso, P.; de Mello, S.M. 1977: Therapeutic evaluation of an imidazole compound R.P. 14539 in intestinal amebiasis Revista do Instituto de Medicina Tropical de Sao Paulo 19(5): 342-348
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Kurdin, A.N.; Ivanov, D.D. 1977: Several aspects of pharmacology and therapeutic use of prostaglandins Terapevticheskii Arkhiv 49(1): 112-119