Application of cefpimizole in obstetrics and gynecology
Usuki, S.; Saito, M.; Miyagawa, S.; Iwasaki, H.
Japanese Journal of Antibiotics 38(4): 921-925
1985
ISSN/ISBN: 0368-2781 PMID: 4032729 Document Number: 257203
Fundamental and clinical studies of a new cephalosporin derivative, cefpimizole (AC-1370), were performed. AC-1370 was relatively efficiently transferred into the uterus and uterine adnexa; it was as well transferred into the tissues as the other cephalosporin derivatives. There seemed to be no specific relation between its blood level and its level in any tissue. In 1 patient treated with AC-1370 for postoperative infection, clinical findings, WBC and CRP improved; the drug was evaluated as effective. Neither hepatic nor renal function was impaired in the patients treated with AC-1370 in the fundamental and clinical studies of the drug.