Leukergy-stimulating factors in polycythemia vera
Fischer, H.
Folia Haematologica 112(4): 580-586
1985
ISSN/ISBN: 0323-4347 PMID: 2414187 Document Number: 255636
In a group of patients with polycythaemia vera (n = 10) a leukocyte activation could be identified in all cases by leukocyte agglomeration (LA). During full remission, LA remained within the normal range in nearly all patients. By means of plasma exchange trials leukocyte activation could be demonstrated to be caused by humoral factors being insensitive to inactivation at 56 degrees C. Factors stimulating leukergy apparently indicate a close relation to the activity of myelopoiesis. Its evidence can be applied as a diagnostic criterion for polycythaemia vera.