Mediators and asthma
Barnes, P.J.
British Journal of Hospital Medicine 34(6): 339-344
1985
ISSN/ISBN: 0007-1064 PMID: 3936563 Document Number: 255144
Several mediators produced by various inflammatory cells have now been implicated in asthma. They may contribute to the pathology of asthma by contracting airway smooth muscle, stimulating mucus secretion, and promoting bronchial oedema and chemotaxis of inflammatory cells. Because many mediators interact, antagonism of any single mediator is unlikely to have a major clinical effect.
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