Local specific IgE production in nasal polyps associated with negative skin tests and serum RAST

Small, P.; Barrett, D.; Frenkiel, S.; Rochon, L.; Cohen, C.; Black, M.; Small, P; Barrett, D; Frenkiel, S; Rochon, L; Cohen, C; Black, M

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Local specific IgE production in nasal polyps associated with negative skin tests and serum RAST

Small, P.; Barrett, D.; Frenkiel, S.; Rochon, L.; Cohen, C.; Black, M.

Annals of Allergy 55(5): 736-739

1985

ISSN/ISBN: 0003-4738

PMID: 4061982

Document Number: 254268

Eighteen of 24 patients undergoing nasal polypectomies demonstrated polyp fluid total IgE higher than corresponding serum values. Allergen-specific IgE was detected in polyp fluid of 19/24 patients. Since only 9/19 had positive skin tests, ten patients had specific IgE locally in polyp tissue which could not be detected systemically.