Preliminary results of a prospective study of microcirculatory disorders in alcoholic fibro-cirrhosis. Relation to hyperestrogenism
Janbon, C.; Coupe, M.; Espitalier, C.; Charras, C.; Dubois, A.
Journal des Maladies Vasculaires 10 Suppl A: 173-175
1985
ISSN/ISBN: 0398-0499 PMID: 4031672 Document Number: 253920
In the course of alcoholic cirrhosis, the low incidence of occlusive arterial diseases in the lower limbs, as well as the analogy in skin lesions between cirrhosis and pregnant women, lead to believe that hyperestrogenism may be common origin of these skin lesions. Research of abnormal microcirculation in the nailfold and oestrogen's receptors have been performed in a cirrhotic (20) and hyperestrogenic (12) population. The capillaroscopic abnormalities have been as follows: fine and short capillaries, oedema slacked circulation, the underlying structure was pale with peripheral halo. These have been observed both in the cirrhotic and hyperestrogenic patients. These oestrogenic receptor in both populations seem mainly localised in the granulosa structure and are more numerous than normal. Capillaroscopic features on the cirrhotic patients were similar to those on hyperestrogenic patients. The presence of oestrogenic receptors in the skin bears no particular significance at the present time.