IgA nephropathy: perspectives on pathogenesis and classification
Emancipator, S.N.; Gallo, G.R.; Lamm, M.E.
Clinical Nephrology 24(4): 161-179
1985
ISSN/ISBN: 0301-0430 PMID: 3905099 Document Number: 252686
IgA nephropathy has received growing attention since its recognition 18 years ago. In this review the salient demographic, clinical and pathologic features are summarized. Next follows a discussion of the pathogenesis of the disease in light of current clinical and experimental data, with a proposal for classification based upon immune response, disordered immunoregulation, and the impairment of clearance of immune complexes.