History of the development of oral rehydration fluids
Sack, R.Bradley.
Journal of the Indian Medical Association 101(6): 360 362-4
2003
ISSN/ISBN: 0019-5847 PMID: 14579982 Document Number: 251211
The development of oral rehydration fluid for the treatment of cholera and other diarrhoeal diseases has been regarded as one of the most important medical advances of the last century. This article summarizes the information on how this achievement was made possible. The development was traced from the historical empiric use of oral fluids for treating diarrhoea, to physiological studies in animals that defined how glucose and sodium were coupled in absorption by the small intestine and finally, to the use of this knowledge in developing the simple effective solutions that were adopted by WHO as the mainstay of diarrhoeal therapy worldwide.
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