Tiapamil--a new calcium antagonist
Opie, L.H.; Muller, C.A.; Thandroyen, F.T.; Lloyd, E.A.; Mabin, T.; Commerford, P.J.; Eichler, H.G.
South African Medical Journal 67(22): 881-883
1985
ISSN/ISBN: 0256-9574 PMID: 3890216 Document Number: 250598
Calcium antagonists are an important new modality in cardiovascular therapy. Tiapamil, a congener of verapamil, is undergoing clinical and laboratory evaluation. We have undertaken experimental studies on the anti-arrhythmic properties of tiapamil, and on the intravenous use of this agent in patients with acute myocardial infarction. Reasons are given for suggesting that tiapamil warrants further clinical evaluation, after which it may join the more established calcium antagonists as a valuable therapeutic agent.