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HIV-1 seroprevalence rates in women and relinquishment of infants to the state in St Petersburg, Russia, 2002

Khaldeeva, N.; Hillis, S.D.; Vinogradova, E.; Voronin, E.; Rakhmanova, A.; Yakovlev, A.; Jamieson, D.J.; Ryder, R.W.

Lancet 362(9400): 1981-1982

2003

ISSN/ISBN: 1474-547X
PMID: 14683660
DOI: 10.1016/s0140-6736(03)15019-2
Document Number: 250441
The effectiveness of rapid HIV-1 testing and nevirapine prophylaxis for HIV-infected mothers without prenatal care has been shown. We found that from 1998 to 2002, HIV-1 seroprevalence in women giving birth in St Petersburg, Russia increased 100-fold: from 0.013% to 1.3% (p<0.0001). HIV-1 seroprevalence was 8% (114 of 1466) in women without prenatal care and 1% (376 of 37645) in those with prenatal care (p<0.0001). All 376 HIV-1-infected women with, and 41% (47 of 114) of HIV-1-infected women without prenatal care received intrapartum antiretroviral therapy (p<0.0001). In women who were HIV-1 positive, 26% (30 of 114) of those without prenatal care and 4% (13 of 371) of those with prenatal care relinquished their infants to the custody of the state, compared with 1% (354 of 37 621) of HIV-1-negative women (p<0.0001).

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